Zecyte 500mg

Abiraterone is sold under brand name  Zecyte 500mg Zecyte 500mg  is exists to type of anti-cancer remedy that will act by decline the androgen production in the body. Androgen is a male... read more
  • Brand: Cipla
  • Brand Name Zecyte
  • Strength 500mg
  • Generic Abiraterone acetate

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ZECYTE 500MG

Zecyte 500mg Description

Abiraterone is sold under brand name Zecyte 500mg

Zecyte 500mg is exists to type of anti-cancer remedy that will act by decline the androgen production in the body. Androgen is a male hormone that can protect the tumor cell in prostate glands.This drug is given by co administration with prednisolone, a steroid which reduce the liability of side effects produced by Abiraterone.

Mechanism of action

Androgens are balance the production of malignant in prostate.

Zecyte 500mg belongs to anti androgen drugs, that causes to suppress the enzyme 17α-hydroxylase C 17, 20-lyase (CYP17), it is involving in androgen conglomerate.

Declined the serum testosterone level.

Reduce the tumor cell occurred.

Pharmacokinetics

Absorption: Time to maximum plasma concentration of Zecyte 500mg tablet takes 12 hours.

Distribution: Maximum bound to the human plasma protein like albumin and alpha-1 acid glycoprotein.

Metabolism: The main two metabolites of Abiraterone in human plasma are Abiraterone sulphate and N-oxide Abiraterone sulphate.

Excretion: The drug mainly excreted in 88% feces and 5% in urine

Half-life of tablet Zecyte 500mgis 12 ± 5 hours.

Side Effects occurred in Zecyte 500mg Tablets

Common effects

Fatigue, Arthralgia, Hypertension, Nausea, edema, Hypokalemia, Diarrhea, vomiting, Cough, headache, Glucocorticoid deficiency, Mineral corticoid deficiency, Hepatotoxicity, Hypertension, Decrease in ka level, Adrenocortical insufficiency

Muscular skeletal and Connective tissue disorders: Joint swelling, discomfort, muscle discomfort

General Disorder: Edema

Cardiac disorders: Hot flush, hypertension, arrhythmias, chest pain, cardiac failure

GIT disorders: Diarrhea, dyspepsia

Infections and Infestation: UTI

Pulmonary disorder: Cough

Renal: Urinary frequency, nocturia

Injuries: Fractures

Dosage And Administration

The prescribed dose of Zecyte is initial as 4 tablets given orally once daily.

The drug Zecyte administrated combination with 5mg prednisolone twice daily in empty stomach.

  • Zecyte Tablets given on an empty stomach.
  • Food should not be taken for at least 2 hours before and at least 1 hour after the dose of Zecyte Tablets is taken.
  • Swallowed whole with water.
  • Chew the tablets or Do not crush

Drug Interaction

Interaction of Zecyte 500mg with dextromethorphan will raises the Cmax and AUC of dextromethorphan

Interaction Zecyte 500mg with strong CYP3A inhibitors or inducers, concomitant use with caution because pharmacokinetics is not evaluated.

Safety And Warning

Any allergy, serious liver disputeor pregnant in patient, Zecyte 500mg therapy should be stopped

Avoid taking of other medications, i.e. prescription, over-the-counter, vitamins, herbal remedies, etc. be sure to inform the doctors before the treatment.

Do not take Aspirin administrated and products containing aspirin till doctor particularly allow the drug.

Overdosage: Zecyte 500mg has no essential antidote, if overdose occurs end treatment with the drug and give general supportive measures such as monitoring arrhythmias and cardiac failure and assess liver function.

Missed Dose

If patient missed the dose of  Zecyte 500mg, that missed dose will be boundand follow the regular dosing agenda.

Pregnancy

Pregnancy category X: while on therapy with Zecyte 500mg tablet if women become pregnant, rapidly stop the drug and give cautionto the women. Zecyte 500mg tablet is not suggested for women.

Lactation

Zecyte 500mg not used in women eliminationin human milk is unknown and the drug effects in the nursing bundle is unknown.

Handling Of Storage

The medicine stored at 15oC-30oC

Keep the stimulantin dry place.

  • Zecyte
  • 500mg
  • Abiraterone acetate
  • 60 tablets
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