Zecyte 250mg

Abiraterone is sold under brand name  Zecyte 250mg Zecyte 250mg  concernto the type of anti-cancer drug that will act by a denythe androgen production in the body. Androgen is a male... read more
  • Brand Name Zecyte
  • Strength 250mg
  • Generic Abiraterone acetate

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ZECYTE 250MG

Zecyte 250mg Description

Abiraterone is sold under brand name Zecyte 250mg

Zecyte 250mg concernto the type of anti-cancer drug that will act by a denythe androgen production in the body. Androgen is a male hormone that can providethe tumor cell in prostate glands.

This prescriptionis given by co-administration with prednisolone, a steroid that reduces the obligationof side effects produced by Abiraterone.

Mechanism of action

Androgens are balancing the production of diseasedin the prostate.

Zecyte 250mg belongs to anti-androgen drugs, that cause to containthe enzyme 17α-hydroxylase C 17, 20-lyase (CYP17), it is implicatein androgen conglomerate.

Depressthe serum testosterone level.

Desistthe tumor cell occurred.

Pharmacokinetics

Absorption: Time to maximum plasma consolidationof Zecyte 250mg tablet takes 12 hours.

Distribution: Maximum obligatedto the human plasma protein like albumin and alpha-1 acid glycoprotein.

Metabolism: The essentialtwo metabolites of Abiraterone in human plasma are Abiraterone sulphate and N-oxide Abiraterone sulphate.

Excretion: The drug mainly secretesin 88% feces and 5% in urine

The half-life of tablet Zecyte 250mg is 12 ± 5 hours.

Side Effects appearin Zecyte 250mg tablets

Common effects

Fatigue, Arthralgia, Hypertension, Nausea, edema, Hypokalemia, Diarrhea, vomiting, Cough, headache, Glucocorticoid deficiency, Mineral corticoid deficiency, Hepatotoxicity,Decrease in a level, Adrenocortical insufficiency

Muscular-skeletal and Connective tissue disorders: Joint swelling, discomfort, muscle discomfort

General Disorder: Edema

Cardiac disorders: Hot flush, hypertension, arrhythmias, chest pain, cardiac failure

GIT disorders: Diarrhea, dyspepsia

Infections and Infestation: UTI

Pulmonary disorder: Cough

Renal: Urinary frequency, nocturia

Injuries: Fractures

DOSAGE AND ADMINISTRATION

The prescribed dose of Zecyte is initial as 4 tablets given orally once daily.

The drug Zecyte administrated a combination with 5mg prednisolone twice daily in an empty stomach.

•         Zecyte Tablets given on an empty stomach.

•         Food should not be taken for at least 2 hours before and at least 1 hour after the dose of Zecyte Tablets is taken.

•         Swallowed whole with water.

•         Chew the tablets or Do not crush

DRUG INTERACTION

Interaction of Zecyte 250mg with dextromethorphan will raise the Cmax and AUC of dextromethorphan

Interaction Zecyte 250mg with strong CYP3A inhibitors or inducers, concomitant use with caution because pharmacokinetics is not evaluated.

SAFETY AND WARNING OF ZECYTE 250MG

Any allergy, serious liver problem or pregnant inpatient, Zecyte 250mg therapy should be stopped

Avoid taking of other medications, i.e. prescription, over-the-counter, vitamins, herbal remedies, etc. be sure to inform the doctors before the treatment.

Do not take Aspirin administrated and products containing aspirin until the doctor particularly allows the drug.

OVERDOSAGE: Zecyte 250mg has no essential antidote If an overdose occurs end treatment with the drug and give general supportive measures such as monitoring arrhythmias and cardiac failure and assess liver function.

MISSED DOSE

If a patient missed the dose of Zecyte 250mg, that missed dose will be skipped and follow the regular dosing schedule.

PREGNANCY

Pregnancy category X: while on therapy with Zecyte 250mg tablet if women become pregnant, immediately stop the drug and give counseling to the women. Zecyte 250mg tablet is not recommended for women.

LACTATION

Zecyte 250mg not used in women excretion in human milk is unknown and the drug effects in the nursing infant are unknown.

HANDLING OF STORAGE

The drug stored at  15oC - 30oC

Keep the drug in a dry place.

  • Zecyte
  • 250mg
  • Abiraterone acetate
  • 120 tablets
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